Caution on Liver Damage and Cymbalta (Jan. 2006)

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New precautions about liver damage have been added to the labeling for Cymbalta (duloxetine), which is used to treat major depressive disorder and diabetic peripheral neuropathic pain. The labeling had already warned of hepatotoxicity from the drug, and cautioned that it should not be prescribed in patients with substantial alcohol use. Now, based on new reports of hepatitis in patients taking Cymbalta, the labeling states that the drug should not be administered to any patients with evidence of chronic liver disease. Additional Information: FDA MedWatch Safety Alert 2005 - Cymbalata (duloxetine hydrochloride). www.fda.gov

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